UNCOVERING INTEGRATIVE STRATEGIES: THE PROMISE OF EGCG IN FIGHTING PROSTATE CANCER
Authors: Alexander Müller, Sophie Schmidt
Published: March 2024
Abstract
<p>Prostate cancer is the most common cancer in males and one of many types of malignancies that are said to be prevented by drinking green tea and Epigallocatechin-3-gallate (EGCG) intervention. However, epidemiological studies have produced conflicting results regarding the anti-cancer effects of EGCG. In recent years, numerous researchers have demonstrated the effectiveness and safety of green tea polyphenols, including EGCG alone and in combination therapies, through <em>in vivo</em> and <em>in vitro</em> studies. Nevertheless, the molecular mechanisms underlying the anticancer potential of EGCG remain poorly understood. To evaluate the prevention and treatment of prostate cancer, it is critical to have a better understanding of the precise mode of action of EGCG against the growth and progression of prostate cancer. With a focus on the molecular mechanisms of action of EGCG, such as influencing tumour growth, apoptosis, androgen receptor signaling, cell cycle, and various malignant behaviors, we present information regarding the anti-cancer effects of EGCG in the prevention and treatment of prostate cancer in this review</p>
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