ANALYTICAL METHOD USING NBSA REAGENT FOR QUANTIFICATION OF PURE AND PHARMACEUTICAL ANTIHISTAMINE DRUGS
Authors: Prasad Verma Meera
DOI: 10.5281/zenodo.17433174
Published: October 2025
Abstract
<p><em>A quick and convenient method has been developed for the micro estimation of antihistamine drugs. 1-5 mg of sample is allowed to react with 10 ml of 0.02 M, N-bromosaccharin solution. Unconsumed reagent can be accurately titrated with 5 ml of 15% KI and 0.02N sodium thiosulphate solution using starch as indicator. SD and CV was calculated for reproducible and accurate result. The accuracy of the method is within <u>+ </u>1 % and possible course of reaction was suggested on the basis of stoichiometry as well as find reaction product</em></p>
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DOI: 10.5281/zenodo.17433174
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