SYSTEMIC LUPUS ERYTHEMATOSUS WITH PRES: A RARE BUT TREATABLE NEUROVASCULAR PRESENTATION
Authors: Arijit Subhasis Chatterjee
DOI: 10.5281/zenodo.17379754
Published: October 2025
Abstract
<p><em>Posterior reversible encephalopathy syndrome (PRES) has been reported in association with hypertension, renal failure, transplantation and immunosuppressives [1]. However, reports of PRES in conjunction with SLE are sparse [2]. Majority of these patients had lupus nephritis and hypertension [3]. Recent reports have shown a stringent association of PRES with hypertension in SLE patients and response to cyclophosphamide-methylprednisolone pulse therapy [4]. Here, we report a rare case of a normotensive patient of SLE presenting with PRES. The patient was treatment-naïve and had significant renal involvement. Her neurologic impairment and overall disease activity improved following treatment with pulse doses of immunosuppressive<u>s</u>. </em></p>
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